Australian Politics Forum - China's covert biological weapons program

Jovial Monk

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Re: China's covert biological weapons program
Reply #1230 - Oct 8^th, 2023 at 4:04pm

I guess the High School Dropout needs to be educated.

1. What are cell walls made of?

The cell membrane is a biological membrane that separates the interior of all cells from the outside environment. The cell membrane is made up of protein and lipid bilayer in all types of cells; animal, plant, bacteria etc.

2. Can the spike get into almost any animal cell?

Quote:

The COVID-19 was quickly discovered to be caused by a coronavirus later named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1], which belongs to the β coronavirus family. It is the seventh known coronavirus to infect humans; four of these coronaviruses (229E, NL63, OC43, and HKU1) only cause slight symptoms of the common cold. Conversely, the other three, SARS-CoV, MERS-CoV, and SARS-CoV-2, are able to cause severe symptoms and even death, with fatality rates of 10%, 37%, and 5%, respectively.The COVID-19 was quickly discovered to be caused by a coronavirus later named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1], which belongs to the β coronavirus family. It is the seventh known coronavirus to infect humans; four of these coronaviruses (229E, NL63, OC43, and HKU1) only cause slight symptoms of the common cold. Conversely, the other three, SARS-CoV, MERS-CoV, and SARS-CoV-2

How does the virus get into cells?
Quote:

SARS-CoV-2 is a single-stranded RNA-enveloped virus [5]. An RNA-based metagenomic next-generation sequencing approach has been applied to characterize its entire genome, which is 29,881 bp in length (GenBank no. MN908947), encoding 9860 amino acids [6]. Gene fragments express structural and nonstructural proteins. The S, E, M, and N genes encode structural proteins, whereas nonstructural proteins, such as 3-chymotrypsin-like protease, papain-like protease, and RNA-dependent RNA polymerase, are encoded by the ORF region [7].

A large number of glycosylated S proteins cover the surface of SARS-CoV-2 and bind to the host cell receptor angiotensin-converting enzyme 2 (ACE2), mediating viral cell entry [8]. When the S protein binds to the receptor, TM protease serine 2 (TMPRSS2), a type 2 TM serine protease located on the host cell membrane, promotes virus entry into the cell by activating the S protein. Once the virus enters the cell, the viral RNA is released, polyproteins are translated from the RNA genome, and replication and transcription of the viral RNA genome occur via protein cleavage and assembly of the replicase–transcriptase complex. Viral RNA is replicated, and structural proteins are synthesized, assembled, and packaged in the host cell, after which viral particles are released (Fig. 1d) [9].

https://www.nature.com/articles/s41401-020-0485-4

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Bobby.

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Re: China's covert biological weapons program
Reply #1231 - Oct 8^th, 2023 at 7:23pm

Monk doesn't know,

https://gyandemic.substack.com/p/how-the-coronavirus-infects-so-many

How does SARS-CoV-2 infect so many different cells in different parts of the body?

This work just came out a few hours ago in two landmark papers that were published in Science. Two groups independently show that the spike of SARS-CoV-2 uses a protein called neuropilin-1 on the surface of human cells to facilitate infection.
Why is this important?

First, because it is another piece of the puzzle in how a respiratory virus can infect tissues and organs in different parts of the body, such as the heart and the brain.

We’ve known for a while now that the virus uses its spike to get access to the cell through the ACE2 receptor. The first step is attachment of the spike. And the second is two-step cutting process (using two cleaver-like enzymes) which prepares the virus to enter the cell.

The two-step process explains why SARS-CoV-2 is better at infecting cells than its forerunner, SARS coronavirus (which had a one-step process). But it didn’t fully explain how the virus accessed cells throughout the body that don’t have many ACE2 receptors.

We've also known for months that the infectiousness of SARS-CoV-2 can't be explained simply by the enhanced presence of the receptor the virus uses to get inside the cell (ACE2). There are other "weaker" interactions that the virus uses too. Now we know that neuropilin-1 plays a major role in one of these interactions.

Second, this work opens up a new line of discovery for drugs that can slow down or even stop infection by blocking the interaction between the viral spike protein and neuropilin-1. An anti-viral treatment, that reduces the ability of the virus to infect human cells may be possible.

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Jovial Monk Gold Member Offline Dogs not cats! Posts: 46657 Gender:	Re: China's covert biological weapons program Reply #1232 - Oct 8^th, 2023 at 7:41pm It can attack any protein in the cell walls and animal cell walls contain protein and lipids.
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Bobby.

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Re: China's covert biological weapons program
Reply #1233 - Oct 8^th, 2023 at 7:57pm

Jovial Monk wrote on Oct 8^th, 2023 at 7:41pm:

It can attack any protein in the cell walls and animal cell walls contain protein and lipids.

Monk,
you don't know and even the scientists don't know:

"But it didn’t fully explain how the virus accessed cells throughout the body
that don’t have many ACE2 receptors."

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Dnarever

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Re: China's covert biological weapons program
Reply #1234 - Oct 8^th, 2023 at 8:05pm

Bobby. wrote on Oct 8^th, 2023 at 1:21pm:

Jovial Monk wrote on Oct 8^th, 2023 at 9:18am:

Yeah “looked like” is not evidence, of course, but it was said.

I believe the virus is natural with the wet market a breeding ground for all sorts of nasties.

You've been told why what you believe is not possible.

It was man made - it's a bio-weapon.

That is about the least likely conclusion. Possible but unlikely.

It is behind both the wet market and from the Lab accidentally among other things. It may even be behind the Wuhan Army Games.

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Bobby.

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Re: China's covert biological weapons program
Reply #1235 - Oct 8^th, 2023 at 8:10pm

Dnarever wrote on Oct 8^th, 2023 at 8:05pm:

Bobby. wrote on Oct 8^th, 2023 at 1:21pm:

Jovial Monk wrote on Oct 8^th, 2023 at 9:18am:

Yeah “looked like” is not evidence, of course, but it was said.

I believe the virus is natural with the wet market a breeding ground for all sorts of nasties.

You've been told why what you believe is not possible.

It was man made - it's a bio-weapon.

That is about the least likely conclusion. Possible but unlikely.

It is behind both the wet market and from the Lab accidentally among other things. It may even be behind the Wuhan Army Games.

Then why did China not allow a proper WHO inquiry?

Why did China delete records?

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Jovial Monk Gold Member Offline Dogs not cats! Posts: 46657 Gender:	Re: China's covert biological weapons program Reply #1236 - Oct 8^th, 2023 at 8:10pm God, you have been told that before! You just don’t retain information, do you?
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Jovial Monk

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Re: China's covert biological weapons program
Reply #1237 - Oct 8^th, 2023 at 8:43pm

Dnarever wrote on Oct 8^th, 2023 at 8:05pm:

Bobby. wrote on Oct 8^th, 2023 at 1:21pm:

Jovial Monk wrote on Oct 8^th, 2023 at 9:18am:

Yeah “looked like” is not evidence, of course, but it was said.

I believe the virus is natural with the wet market a breeding ground for all sorts of nasties.

You've been told why what you believe is not possible.

It was man made - it's a bio-weapon.

That is about the least likely conclusion. Possible but unlikely.

It is behind both the wet market and from the Lab accidentally among other things. It may even be behind the Wuhan Army Games.

Wet markets started the Spanish Flu, SARS-CoV-1 and SARS–CoV–2.

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Bobby. Gold Member Offline Australian Politics Posts: 104609 Melbourne Gender:	Re: China's covert biological weapons program Reply #1238 - Oct 8^th, 2023 at 8:47pm Jovial Monk wrote on Oct 8^th, 2023 at 8:10pm: God, you have been told that before! You just don’t retain information, do you? China had lots to hide.
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Jovial Monk Gold Member Offline Dogs not cats! Posts: 46657 Gender:	Re: China's covert biological weapons program Reply #1239 - Oct 8^th, 2023 at 9:08pm It was a matter of face, which you had been told before, dumbarse.
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Bobby. Gold Member Offline Australian Politics Posts: 104609 Melbourne Gender:	Re: China's covert biological weapons program Reply #1240 - Oct 8^th, 2023 at 9:24pm Jovial Monk wrote on Oct 8^th, 2023 at 9:08pm: It was a matter of face, which you had been told before, dumbarse. China has lots to hide as they are guilty. You are guilty for being an apologist of the CCP - and a Marxist.
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Jovial Monk Gold Member Offline Dogs not cats! Posts: 46657 Gender:	Re: China's covert biological weapons program Reply #1241 - Oct 8^th, 2023 at 9:41pm You can’t fix stupid. Against stupidity the gods themselves contend in vain.
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Bobby. Gold Member Offline Australian Politics Posts: 104609 Melbourne Gender:	Re: China's covert biological weapons program Reply #1242 - Oct 8^th, 2023 at 9:44pm Jovial Monk wrote on Oct 8^th, 2023 at 9:41pm: You can’t fix stupid. Against stupidity the gods themselves contend in vain. China and Monk are as guilty as sin.
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Jovial Monk Gold Member Offline Dogs not cats! Posts: 46657 Gender:	Re: China's covert biological weapons program Reply #1243 - Oct 8^th, 2023 at 9:47pm QED.
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Bobby. Gold Member Offline Australian Politics Posts: 104609 Melbourne Gender:	Re: China's covert biological weapons program Reply #1244 - Oct 13^th, 2023 at 6:20am Rand Paul is gunna get Fauci. 'BOMBSHELL REVELATION': Rand Paul says he has evidence to 'bring down Fauci'
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