But the wet market was the source of the pandemic!
Quote:Wuhan market was epicentre of pandemic’s start, studies suggest
Report authors say that the coronavirus SARS-CoV-2 jumped to people from animals sold at the market on two occasions in late 2019 — but some scientists want more definitive evidence.
See how as one good paper got published other scientists posted results of their studies, all pointing to the wet market.
Quote:Scientists have released three studies that reveal intriguing new clues about how the COVID-19 pandemic started. Two of the reports trace the outbreak back to a massive market that sold live animals, among other goods, in Wuhan, China1,2, and a third suggests that the coronavirus SARS-CoV-2 spilled over from animals — possibly those sold at the market — to humans at least twice in November or December 20193. Posted on 25 and 26 February, all three are preprints, and so have not been published in a peer-reviewed journal.
Lovely market!
Quote:One major finding reported by Andersen and colleagues is the mapping of five positive samples from the market to a single stall that sold live animals, and, more specifically, to a metal cage, to carts used to move animals and to a machine used to remove birds’ feathers2. One of the report’s co-authors, virologist Eddie Holmes at the University of Sydney in Australia, had been to this stall in 2014 and snapped photographs — included in this study — of a live raccoon dog in a metal cage, stacked above crates of poultry, with the whole assembly sitting on top of sewer drains. Notably, in the study by researchers at the China CDC, sewage at the market tested positive for SARS-CoV-2.
This filthy market is not your suburb supermarket! Anyway, back to the story:
Quote:Scientists have released three studies that reveal intriguing new clues about how the COVID-19 pandemic started. Two of the reports trace the outbreak back to a massive market that sold live animals, among other goods, in Wuhan, China1,2, and a third suggests that the coronavirus SARS-CoV-2 spilled over from animals — possibly those sold at the market — to humans at least twice in November or December 20193. Posted on 25 and 26 February, all three are preprints, and so have not been published in a peer-reviewed journal.
These analyses add weight to original suspicions that the pandemic began at the Huanan Seafood Wholesale Market, which many of the people who were infected earliest with SARS-CoV-2 had visited. The preprints contain genetic analyses of coronavirus samples collected from the market and from people infected in December 2019 and January 2020, as well as geolocation analyses connecting many of the samples to a section of the market where live animals were sold. Taken together, these lines of evidence point towards the market as the source of the outbreak — a situation akin to that seen in the epidemic of severe acute respiratory syndrome (SARS) in 2002–04, for which animal markets were found to be ground zero — says Kristian Andersen, a virologist at the Scripps Research Institute in La Jolla, California, and an author on two of the reports. “This is extremely strong evidence,” he says.
Quality of evidence is important!
Quote:However, none of the studies contains definitive evidence about what type of animal might have harboured the virus before it spread to humans. Andersen speculates that the culprits could be raccoon dogs, squat dog-like mammals used for food and their fur in China. One of the studies he co-authored2 suggests that raccoon dogs were sold in a section of the market where several positive samples were collected. And reports4 show that the animals can harbour other types of coronavirus.
Nevertheless, some virologists say that the new evidence pointing to the Huanan market doesn’t rule out an alternative hypothesis. They say that the market could just have been the location of a massive amplifying event, in which an infected person spread the virus to many other people, rather than the site of the original spillover.
E.g:
Quote:“Analysis-wise, this is excellent work, but it remains open to interpretation,” says Vincent Munster, a virologist at the Rocky Mountain Laboratories, a division of the National Institutes of Health in Hamilton, Montana. He says that searching for SARS-CoV-2 and antibodies against it in blood samples collected from animals sold at the market, and from people who sold animals at the market, could provide more-definitive evidence of COVID-19’s origins.
So we have evidence that the wet market DID have COVID19 in animal cages etc. Now to tie the origin down further:
Quote:Researchers then collected samples from poultry, snakes, badgers, giant salamanders, Siamese crocodiles and other animals sold there. They also swabbed drains, cages, toilets and vendors’ stalls in search of the pathogen. Following an investigation led by the World Health Organization (WHO), researchers released a report in March 2021 showing that all of the nearly 200 samples collected directly from animals were negative, but that around 1,000 environmental samples from the stalls and other areas of the market were positive.
cont’d