Still waiting for some proof that SARS-CoV-2 is now just a "mild respiratory virus".
Meanwhile, here's more proof that it isn't:
COVID-19 raises the stakes for heart attacks, strokes, and even death long after infection, new study findsThis one is paywalled but I found a way around it.
Quote:Practically from the beginning of the COVID-19 pandemic, researchers and medical experts feared–and often loudly warned–that the virus wasn’t like other infections that people might encounter during, say, flu season. SARS-CoV-2 was different. It was worse. And the potential long-term effects, as we reported two years ago, were even more worrisome.
A new large-scale study puts those longer-range concerns into bold relief. The results are as unforgiving as many experts had hypothesized.
The study, involving nearly a quarter-million adults, found that those with any type of COVID-19 infection in 2020 had twice the risk of suffering a major cardiac event—a heart attack, stroke, or even death—in the three years after a diagnosis than those who weren’t infected.
People whose infections were severe enough to warrant hospitalization faced nearly a four times greater risk of a major cardiac event or death than the uninfected group.
“These findings are undeniable and extremely troubling,” says David Putrino, the director of the Cohen Center for Recovery from Complex Chronic Illness at Mount Sinai School of Medicine. “The significance of this work is that our current public health policy surrounding COVID-19 is inadequate. People need to be informed of the risks they are incurring to their long-term health by being repeatedly infected with SARS-CoV-2.”
There is a chilling truth to those words. While experts and major medical institutions still find themselves debunking myths about the virus and the vaccines developed to fight it, the longer-term research tells a story of lives irrevocably altered by COVID-19 infections and argues strongly for vaccination and other mitigations against the virus.
The study was published Oct. 9 in the American Heart Association’s peer-reviewed journal Arteriosclerosis, Thrombosis and Vascular Biology. The report’s authors and researchers analyzed data from the U.K. Biobank system, including the data for more than 8,000 adults who had a positive lab test for COVID-19 in 2020 and another 2,000 or so whose cases required hospitalization. Results were compared with nearly 220,000 adults in the database who were not diagnosed with COVID-19 during that time.
In the nearly three years following the acute infection in 2020, the study’s authors found double the risk of heart attack, stroke, and death compared with the uninfected group. Somewhat surprisingly, the elevated risks did not abate over the three years of study, suggesting a problematic staying effect.
“The two-fold increased risk observed in year one following infection was also seen in year two, and even year three,” says study author Stanley Hazen, chair of the Department of Cardiovascular and Metabolic Sciences at the Cleveland Clinic. “This was seen in all subjects independent of age, sex, or risk factors for cardiac disease.” (The ages of those in the study ranged from 50 to 86, with an average age of 67.)
What’s more, in a subset analysis of hospitalized cases without known heart disease, infection with the virus raised the risk for heart attack, stroke, or death to the same levels as individuals who had a history of heart disease, diabetes, or peripheral artery disease (PAD)—but not COVID-19.
“This is why we refer to COVID as a coronary artery disease risk equivalent,” says Hooman Allayee, principal investigator of the study and a professor at USC’s Keck School of Medicine in Los Angeles. “Getting severe COVID is just as bad for heart attacks and strokes as having pre-existing heart disease.”
Those I interviewed were quick to note a critical distinction and key limitation of the study: None of the individuals was vaccinated at the time of their infection, as COVID-19 vaccines were not available in 2020.
“The study didn’t look at the effects of COVID-19 vaccination on a person’s cardiovascular risk,” Hazen says. “I suspect that it would be protective, because vaccines usually keep COVID infections from becoming severe.”
To be continued...